New UK SACT Board National Intrathecal and Intraventricular SACT Guidance

Dear colleagues,

We are pleased to share the newly published UK SACT Board National Guidance on the Safe Administration of Systemic Anti-Cancer Therapies via the Intrathecal or Intraventricular Routes.

This guidance represents an important national update to the arrangements for the safe delivery of intrathecal and intraventricular SACT. It replaces previous Department of Health national guidance and the relevant 2014 Manual for Cancer Services chemotherapy measures, reflecting developments in clinical practice, workforce models, governance and patient safety.

The guidance sets out expectations across governance, local policies, competency and training, prescribing, verification, dispensing, storage, issuing, checking and administration.

We would encourage all organisations delivering intrathecal or intraventricular SACT to review the guidance and consider its implications for their local policies, governance arrangements and clinical practice.

The guidance can be accessed here: UK SACT Board National Guidance

We would like to thank everyone who contributed to the development, consultation and review of this important piece of national guidance.

Please circulate this publication widely across relevant cancer, haematology, pharmacy, nursing, medical, governance and SACT teams.

UK SACT Board

Latest News

By BOPA Executive Committee on 9th November 2026

BOPA members flying the flag for cancer pharmacy at ESMO 2026

It was fantastic to see BOPA members representing cancer pharmacy at ESMO Congress 2026 in Madrid, which brought together the global cancer community from 23 to 27 October to share…

Read article
By BOPA Executive Committee on 30th October 2026

Publication of Pharmaceutical Technology and Pharmacology of Parenteral Oncology Drugs

We are delighted to recognise the recent publication of Pharmaceutical Technology and Pharmacology of Parenteral Oncology Drugs, a new book bringing together expertise from oncology pharmacy professionals across the world.…

Read article
By BOPA Executive Committee on 30th October 2026

Acute and Supportive Oncology Clinical Consensus Statement

BOPA welcomes the Acute and Supportive Oncology Clinical Consensus Statement, to which we were pleased to contribute. It will be a benchmark for the sector, bringing direction and consistency as…

Read article
By BOPA, COSA, CAPhO & ISOPP on 13th October 2026

International Debate Webinar: Eastern and Western Medicine Can Co-exist – part of London Global Cancer Week 2026

Monday 2 November 2026 | 21:00 GMT (check your local time) Part of London Global Cancer Week 2026 Can Eastern and Western medicine co-exist in modern cancer care? Or do…

Read article